31 CMRs have been prohibited for use in cosmetics by the European Commission

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Aug 03, 2023 | 31 CMRs have been prohibited for use in cosmetics by the European Commission

CMRs Cosmetic Act

On 19 July 2023, the European Commission amended Regulation (EC) No 1223/2009 of the European Parliament. The new regulation will prohibit the use of 31 carcinogenic, mutagenic, or toxic for reproduction (CMR) substances in cosmetic products. The amendment comes into force on 9 August 2023 and is applicable from 1 December 2023.

The EU Commission wants to ensure legal certainty and high human health protection. All CMR substances would be included in the prohibited substances list of Regulation (EC) No 1223/2009 (Annex II) and deleted from the restricted or allowed substances lists. If conditions are met, the lists of restricted or allowed substances would be amended accordingly.

The legislation, officially published in the EU Journal on 20 July, adds the compounds to the list of restricted substances in Annex II of the Cosmetic Products legislation. The published regulation is available here.

Annex II to Regulation (EC) No 1223/2009 is amended as follows:

Replacement of Reference No. 1024 as follows:

 

Sr. No.

Reference No.

Substance name

1

1024

2-ethylhexanoic acid and its salts with the exception of those specified elsewhere in Annex VI to Regulation (EC) No 1272/2008

The following substances are prohibited:

 

Sr. No.

Reference No.

Substance name
  1.  

1695

Ammonium bromide
  1.  

1696

Dibutyltin bis(2-ethylhexanoate)
  1.  

1697

Dibutyltin di(acetate)
  1.  

1698

Tellurium dioxide
  1.  

1699

Barium diboron tetraoxide
  1.  

1700

2,2-dimethylpropan-1-ol,tribromo derivative; 3-bromo-2,2-bis(bromomethyl)propan-1-ol
  1.  

1701

2,4,6-tri-tert-butylphenol
  1.  

1702

4,4’-sulphonyldiphenol; bisphenol S
  1.  

1703

Benzophenone
  1.  

1704

Quinoclamine (ISO); 2-amino-3-chloro-1,4-naphthoquinone
  1.  

1705

Perfluoroheptanoic acid; tridecafluoroheptanoic acid
  1.  

1706

methyl N-(isopropoxycarbonyl)-L-valyl-(3RS)-3-(4-chlorophenyl)-β-alaninate; valifenalate
  1.  

1707

6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid, sodium and tris(2-hydroxyethyl)ammonium salts
  1.  

1708

6-[(C10-C13)-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
  1.  

1709

6-[C12-18-alkyl-(branched, unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
  1.  

1710

Theophylline; 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
  1.  

1711

1,3,5-triazine-2,4,6-triamine; melamine
  1.  

1712

Fluopicolide (ISO); 2,6-dichloro-N-[3-chloro-5-(trifluoromethyl)-2-pyridylmethyl]benzamide
  1.  

1713

N-(2-nitrophenyl)phosphoric triamide
  1.  

1714

N-(5-chloro-2-isopropylbenzyl)-N-cyclopropyl-3-(difluoromethyl)-5-fluoro-1-methyl-1H-pyrazole-4-carboxamide; isoflucypram
  1.  

1715

Reaction mass of 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9RS)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide and 3-(difluoromethyl)-1-methyl-N-[(1RS,4SR,9SR)-1,2,3,4-tetrahydro-9-isopropyl-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide [≥ 78 % syn isomers ≤ 15 % anti isomers relative content]; isopyrazam
  1.  

1716

Margosa, ext. [from the kernels of Azadirachta indica extracted with water and further processed with organic solvents]
  1.  

1717

Cumene
  1.  

1718

2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate;
  1.  

1719

Pentapotassium 2,2’,2’’,2’’’,2’’’’-(ethane-1,2-diylnitrilo)pentaacetate
  1.  

1720

N-carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid); Pentetic Acid (INCI)
  1.  

1721

Pentasodium (carboxylatomethyl)iminobis(ethylenenitrilo)tetraacetate; Pentasodium Pentetate (INCI)
  1.  

1722

Acetamiprid (ISO); (1E)-N-[(6-chloropyridin-3-yl)methyl]-N’-cyano-N-methylethanimidamide; (E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine
  1.  

1723

Pendimethalin (ISO); N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidene
  1.  

1724

Bentazone (ISO); 3-isopropyl-2,1,3-benzothiadiazine-4-one-2,2-dioxide

The commission has also updated the substances list in CLP Annex VI during the 18th adaptation to technical progress (ATP) in May 2023.

We acknowledge that the above information has been compiled from Official Journal of European Union

Originally published on Global Product Compliance.

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